Healthy Teeth, Healthy Heart
A recent study published in Trends in Endocrinology and Metabolism on April 16…
Oral infections are the most common diseases of humankind and are also a key risk factor for heart disease, which is the leading cause of death worldwide. In a review article published in Trends in Endocrinology and Metabolism on April 16, researchers summarize the latest clinical evidence supporting a link between oral infections, which are caused by the bacteria in our mouth, and heart disease, and they emphasize the important role of inflammation in both of these conditions.
Inflammation plays a major role both in oral infections such as periodontitis and in cardiovascular disease. However, over-the-counter nonsteroidal anti-inflammatory drugs such as ibuprofen can produce significant cardiovascular side effects, which means it is crucial that we consider alternative therapies. A high dose of a commonly prescribed cholesterol-lowering medication, atorvastatin, which boosts blood levels of anti-inflammatory molecules called lipoxins and resolvins, prevents both periodontal and cardiovascular inflammation and reverses existing disease in humans. This is exciting and promising because lipoxins and resolvins also have the advantage of naturally controlling inflammation without suppressing the immune system.